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In regular honey, the filtration process that gives it that bright, consumer-friendly look and a liquid, drizzle-safe texture also strips honey of most of its beneficial byproducts such as pollen, antioxidants and enzymes. “Processed and regular honey is usually just used and seen as a source of sugar.” Antioxidants, which are present in large amounts of honey, making it a food with great antioxidant potential, are free radical scavengers that reduce formation or neutralize free radicals. A comparative analysis of the total phenol content and antioxidant potential of commercially available common honey was conducted together with Tualang honey from Malaysia. Biochemical analyses revealed a significantly high phenol content in Tualang honey. Therefore, the beneficial antioxidant properties of Tualang honey may be important for human nutrition and health.

Regardless of these factors, honey still contains healthy compounds, such as antioxidants, amino acids, and vitamins. It’s vital that the honey you use contains your healthy bacteria to be effective. Raw honey, which comes straight from the hive, contains healthy bee pollen, bee propolis and many antioxidants. Dark honey varieties have a higher number of antioxidants and activate your immune system.

Melon honey presented the highest amount of phenols, flavonoids, amino acids and proteins, as well as antioxidant capacity in relation to Manuka honey. Both melon honey and Manuka honey induced cytotoxicity and cell death regardless of dose and time in human and metastatic colon adenocarcinoma cells. The results indicate that melon honey and Manuka honey can induce inhibition of cell growth and generation of reactive oxygen species in adenocarcinoma of colon and metastatic cells, which may be due to the presence of phytochemicals with antioxidant properties. These results suggest a potential chemopreventive agent for colon cancer; In addition, honey can improve the action of other substances already used in the treatment of cancer. In addition to being used as food, honey has been used as an alternative medicine for thousands of years. However, the properties and appearance of honey vary greatly depending on the flower source in which the bee collects nectar, so some honey also has strong antioxidant and anti-inflammatory activity.

One study found that the antioxidants in buckwheat honey were detectable in blood plasma, showing that eating honey could improve antioxidant activity in the body. These compounds effectively reduce oxidative stress and help clear free radicals inside. The accumulation of free radicals can cause serious health problems, such as cancer, diabetes and heart disease, etc.

Recently, there have been several studies, mainly in vitro, that show the effectiveness of honey for various medical purposes due to its components and its antibacterial, anti-inflammatory, antioxidant, antiviral, antifungal and anticancer properties. Honey offers many medicinal uses described in traditional medicine, in addition to the fact that it is often used as a sweetener. The composition of honey varies depending on the flower source, seasonal and environmental factors, as well as the processing techniques used.

Apoptosis was done by manuka honey which was also involved in PARP activation, DNA fragmentation and loss of Bcl-2 expression. The apoptotic properties of honey make it a possible natural substance as an anticancer agent, as many chemotherapeutic agents currently used are apoptosis-inducing agents. “Simply put, raw honey is honey just like found in the hive,” explained Amy Shapiro, MS, RD, CDN and founder of Real Nutrition. Raw honey is harvested directly from the honeycomb and then sieved to remove dirt, wax and other dirt before being bottled. Unlike regular honey, raw honey skips the pasteurization or filtration process, resulting in its characteristic cloudy appearance.

This causes an osmotic effect that prevents the growth of bacteria, this effect literally works by drying out the bacteria. Another type of antibacterial property of honey was called inhibition by Dold in 1940. And in 1963, Jonathan White proposed that this inhibitory effect described in 1940 was due to the fact that the hydrogen peroxide produced and accumulated in dilute honey, which we know today, is a byproduct of the formation of gluconic acid by the enzyme glucose oxidase. Gesund bleiben Current studies show that honey can exert anticancer effects through various mechanisms. Research has shown that honey has anticancer properties due to its interference with multiple cell signaling pathways, including induction of apoptosis, antimutagenic, antiproliferative, and anti-inflammatory pathways. In addition, honey can inhibit various forms of tumor in animal modeling, including breast cancer, carcinoma, melanoma, colon carcinoma, liver cancer, and bladder cancer.

Honey induces the expression of p53, caspase 3 and proapoptotic protein Bax and also negatively regulates the expression of the antiapoptotic protein Bcl2. Honey produces ROS, which leads to the activation of p53 and p53, in turn modulates the expression of pro- and anti-apoptotic proteins such as Bcl-2 and Bax. Oral administration of honey increases the expression of the pro-apoptotic protein Bax and also reduces the expression of the anti-apoptotic protein Bcl-2 in the tumor tissue of Wistar rats. Intravenous injection of manuka honey works its apoptotic effect on cancer cell lines through the involvement of caspase 9, which in turn activates caspase-3, the executive protein.

Honey induces leukocytes to release cytokines, which initiates tissue repair cascades. Stimulation of other properties of the immune response by honey (proliferation of B and T lymphocytes and phagocyte activity) has also been reported. Much evidence suggests the use of honey in the control and treatment of acute wounds and for mild to moderate superficial and partial thickness burns. While some studies have suggested the efficacy of honey in relation to the treatment of leg wounds and ulcers, more studies are needed to bolster the current evidence. Honey, although it is a widely available substance that offers many health benefits, bees require a lot of hard work to prepare. Bees after collecting nectar from seasonal flowers release it to their honeycombs and vigorously and robustly fan out their wings to extract excess moisture, which helps extend the shelf life of honey.